Product Name:
MONOCLONAL ANTI-BETA-ACTIN antibody produced in mouse, clone
137CT26.1.1, IgG fraction of antiserum, buffered aqueous solution
biological source:
mouse
Quality Level: 100
antibody form: IgG
fraction of antiserum
antibody product type:
primary antibodies
clone: 137CT26.1.1,
monoclonal
form: buffered
aqueous solution
mol wt: 41737 Da
species reactivity:
mouse, human
technique(s):
immunofluorescence: 1:10-1:50
immunohistochemistry: 1:25
western blot: 1:1000
isotype: IgG1κ
NCBI accession no.:
NP_001092.1
UniProt accession no.:
P60709
shipped in: wet
ice
storage temp.: −20°C
target post-translational modification: unmodified
Gene Information: human
... ACTB(60)
General description
β-actin (ACTB), a member of the actin multigene family, is
an isoform of actin-associated with non-muscle cells. ACTB is a housekeeping
gene mapped to human chromosome 7p22.1.
Application
Monoclonal Anti-Beta-Actin antibody produced in mouse has
been used in western blotting at a dilution of 1:1000.
Biochem/physiol Actions
β-actin (ACTB) forms the core of the cell cytoskeleton. The
polymerization of β-actin is essential for cell physiology. It may serve as a
potential chemotherapeutic agent. Mutation in the ACTB gene is implicated
in sensory hearing loss, delayed-onset generalized dystonia and a combination
of ventral midline malformations. A loss-of-function mutation in the ACTB gene
may cause intellectual disability.
Physical form
Supplied in PBS with 0.09% (W/V) sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company
documentation accompanying the product(s), our products are intended for
research use only and are not to be used for any other purpose, which includes
but is not limited to, unauthorized commercial uses, in vitro diagnostic uses,
ex vivo or in vivo therapeutic uses or any type of consumption or application
to humans or animals.
