biological source:
rabbit
Quality Level: 100
Conjugate: unconjugated
antibody form: affinity
isolated antibody
antibody product type:
primary antibodies
clone: polyclonal
form: buffered
aqueous solution
mol wt: antigen
22 kDa
species reactivity:
human, rat, mouse
concentration: ~1 mg/mL
technique(s):
ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.:
O95471
UniProt accession no.:
O95471
shipped in: wet
ice
storage temp.: −20°C
target post-translational modification: unmodified
Gene Information: human
... CLDN7(1366)
General description
Anti-Claudin 7 Antibody detects endogenous levels of total
Claudin 7 protein.
Claudin 7 is a tight junction membrane protein that belongs
to claudins (cld) family. It is upregulated at high level in the upper
gastrointestinal tract and the liver. It is located on human chromosome 17p13.
Immunogen
The antiserum was produced against synthesized peptide
derived from human Claudin 7.
Immunogen Range: 162-211
Biochem/physiol Actions
In HCC827 and NCI-H358 lung cancer cells, suppression of
claudin-7 decreases the expression of integrin β1. Claudins are important
constituents of tight junctions (TJ) in the upper region of epithelial cells.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the
antibody does not perform in your application, we will issue a full credit or
replacement antibody. Learn
more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and
Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company
documentation accompanying the product(s), our products are intended for
research use only and are not to be used for any other purpose, which includes
but is not limited to, unauthorized commercial uses, in vitro diagnostic uses,
ex vivo or in vivo therapeutic uses or any type of consumption or application
to humans or animals.
