biological source:
rabbit
Quality Level: 100
Conjugate: unconjugated
antibody form: affinity
isolated antibody
antibody product type:
primary antibodies
clone: polyclonal
form: buffered
aqueous solution
mol wt: antigen
24 kDa
species reactivity:
human, mouse
concentration: ~1 mg/mL
technique(s):
ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.:
P57739
UniProt accession no.:
P57739
shipped in: wet
ice
storage temp.: −20°C
target post-translational modification: unmodified
Gene Information: human
... CLDN2(9075)
General description
Anti-Claudin 2 Antibody detects endogenous levels of total
Claudin 2 protein.
Claudin-2 is one of the pore-forming claudins. It is a
member of the claudin family of proteins. Claudin-2 is present in the proximal
tubules. It is mapped to human chromosome Xq22.
Immunogen
The antiserum was produced against synthesized peptide
derived from human Claudin 2.
Immunogen Range: 181-230
Application
Applications in which this antibody has been used
successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry
(1 paper)
Biochem/physiol Actions
The tetraspan membrane protein encoded by claudin multigene
controls paracellular permeability and maintaining cell polarity in epithelial
and endothelial cell sheets. In MDCK (madin-darby canine kidney cells) II
cells, claudin-2 participates in the generation of aqueous pores with high
conductance.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the
antibody does not perform in your application, we will issue a full credit or
replacement antibody. Learn
more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and
Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company
documentation accompanying the product(s), our products are intended for
research use only and are not to be used for any other purpose, which includes
but is not limited to, unauthorized commercial uses, in vitro diagnostic uses,
ex vivo or in vivo therapeutic uses or any type of consumption or application
to humans or animals.
