biological source:
synthetic
Quality Level: 200
Description: histological
grade
Form: liquid
refractive index: n20/D
1.52
viscosity: 1200-1800 mPa.s(20 °C)
solubility: water:
practically insoluble
density: 0.94-0.97 g/L
application(s):
hematology
histology
storage temp.: room
temp
General description
DPX (Distyrene, Plasticizer, and Xylene) is a widely
utilized mounting medium for immunohistology, specifically designed to be
compatible with various detection methods. Introduced in 1939, DPX has become
the routine mountant of choice due to its effectiveness in preserving
histological stains and providing clear visualization of tissue samples. This
mounting medium is a mixture of distyrene (a polystyrene), a plasticizer
(initially tricresyl phosphate, now modified to dibutyl phthalate), and xylene,
making it a versatile option for histological applications.[1]
Application
DPX Mountant for histology is suitable for use as a slide
mountant to fix sections. It serves as a mounting media for viewing slides with
H&E (Hematoxylin-Eosin), Nissl staining, and Masson-Goldner stained
samples.DPX Mountant for histology has been used for:
- Hematoxylin
and Eosin Staining to view the overall muscle structure[2]
- immunohistochemical
analysis and visualization Ki-67 and Bcl-2 expression levels in
cardiomyocytes, cardiac fibroblasts, and vascular endothelial cells of
heart tissue[3]
- -preserving
immunostained brain sections on gelatin-coated slides after histological
processing, ensuring clear visualization of target proteins such as
tyrosine hydroxylase (TH) and neuronal nuclei (NeuN) during microscopy
analysis[4]
- preserving
mount histological sections, such as those from cerebella stained with
hematoxylin-eosin or cresyl violet