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  3. Sigma-Aldrich® Pyridoxal 5′-phosphate hydrate powder, BioReagent, suitable for cell culture, 1G

Sigma-Aldrich® Pyridoxal 5′-phosphate hydrate powder, BioReagent, suitable for cell culture, 1G

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Empirical Formula (Hill Notation):  C8H10NO6P · xH2O

CAS Number:  853645-22-4

Molecular Weight:  247.14 (anhydrous basis)

Beilstein:  234749

EC Number:  200-208-3

MDL number:  MFCD00006333

UNSPSC Code:  12352205

PubChem Substance ID:  24898438

NACRES:  NA.75

product line:  BioReagent

Quality Level:  200

Assay:  ≥98%

Form:  powder

mol wt:  Mw 247.14 g/mol

technique(s): cell culture | mammalian: suitable

color:  off-white to yellow-brown

mp:  140-143 °C

solubility:  1 M HCl: soluble 50 mg/mL, clear, colorless to light yellow-green

storage temp.:  −20°C

SMILES string:  CC1=NC=C(COP(O)(O)=O)C(C([H])=O)=C1O

InChI:  1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)

InChI key:  NGVDGCNFYWLIFO-UHFFFAOYSA-N

General description

Pyridoxal-phosphate (PLP, pyridoxal-5′-phosphate, P5P) is a prosthetic group of some enzymes. It is the active form of vitamin B6, which comprises three natural organic compounds, pyridoxal, pyridoxamine and pyridoxine. PLP acts as a coenzyme in all transamination reactions, and in some decarboxylation and deamination reactions of amino acids.

Application



  • Hierarchical Surface Architecture of Hemodialysis Membranes for Eliminating Homocysteine Based on the Multifunctional Role of Pyridoxal 5′-phosphate.: Discusses the development of advanced hemodialysis membranes using pyridoxal 5′-phosphate, highlighting its role in reducing homocysteine levels, which could contribute to improved outcomes for dialysis patients (Jiang P et al., 2020).