Application
Sodium pyruvate has been used as a component in maturation
medium for oocyte evaluation.[1][2][3][4]
Sodium pyruvate is used by cells as an easily accessible
carbohydrate source. Additionally, it is involved with amino acid metabolism
and initiates the Kreb′s cycle. The 100 mM solution should be diluted 1:100 for
most cell culture applications.
Biochem/physiol Actions
Sodium pyruvate is known to be an effective therapeutic
target for type II citrullinaemia which is characterized by
hyperammonaemia.[5] In vivo studies proves that sodium
pyruvate has protective function against hemorrhagic shock by preventing lipid
peroxidation, NAD+ reduction and cleavage of poly(ADP-ribose)
polymerases.[6] Sodium pyruvate is also known to possess anti-inflammatory
action and might show improvement in chronic lung disorder.[7]
Legal Information
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