General description
L-Ascorbic acid 2-phosphate sesquimagnesium salt hydrate,
also known as Magnesium Ascorbyl Phosphate (MAP), is a stable derivative of
vitamin C (L-ascorbic acid). MAP is applied in various research domains,
including emulsion-based experiments, biocatalytic dephosphorylation, cell
differentiation, and tissue engineering. Its versatile utility extends to gene
repression, transcriptional studies, and investigations related to growth
factors. In cell biology, MAP demonstrates potential applications in inducing
morphological changes in cultured cells, influencing cell death pathways.
Moreover, MAP plays a pivotal role in metabolomics and biochemical research.
Acting as an antioxidant, it effectively scavenges free radicals, offering
protection against oxidative damage. Its anti-inflammatory properties
contribute to the reduction of inflammation, and studies have indicated its
ability to stimulate collagen production. Additionally, MAP serves as a
chelating agent, further expanding its applications in various research
studies. The multifaceted nature of MAP makes it a valuable tool in scientific
investigations, contributing to advancements in cell biology, metabolomics, and
biochemical research.
Application
L-Ascorbic acid 2-phosphate sesquimagnesium salt hydrate has
been used in mesenchymal stem cells (MSC) expansion medium to incubate
scaffolds,[1] in Dulbecco′s modified eagle medium (DMEM) for culturing
human umbilical cord cells[2] and mesenchymal stem cells.[3]
Biochem/physiol Actions
L-Ascorbic acid 2-phosphate (AA2P) is used in biocatalytic
dephosphorylation for electric power generation and electrochemical detection
assays. L-Ascorbic acid 2-phosphate may be used in cell differentiation and
tissue engineering applications. Asc-2P is used in studies of gene repression,
such as the repression of dihydrotestosterone-induced dickkopf-1 expression.
Features and Benefits
- Can
be used in Cell Biology, Metabolomics and Biochemical research
- High-quality
compound suitable for multiple research applications
Other Notes
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