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Sigma-Aldrich® (−)-Epicatechin ≥98% (HPLC), from green tea

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Empirical Formula (Hill Notation):  C15H14O6

CAS Number:  490-46-0

Molecular Weight:  290.27

Beilstein:  92760

EC Number:  207-710-1

MDL number:  MFCD00075648

UNSPSC Code:  12352205

PubChem Substance ID:  24894538

NACRES:  NA.77

biological source:  green tea

Quality Level:  200

Assay:  ≥98% (HPLC)

Mp:  240 °C (dec.) (lit.)

application(s):

metabolomics

vitamins, nutraceuticals, and natural products

storage temp.:  2-8°C

SMILES string:  O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3

InChI:

1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15-/m1/s1

InChI key:   PFTAWBLQPZVEMU-UKRRQHHQSA-N

Gene Information:  human ... BACE1(23621), CYP1A2(1544)

General description

Epicatechin is a flavanol, that belongs to the class of secondary, polyphenolic plant metabolites.[1]

Application

(-)-Epicatechin has been used:


  • to examine its biological effects in cell lines from human gender-specific cancers[2]
  • to study its antiviral activity[3]
  • to test its ability to regenerate this enzymatic activity both in vitro at the isolated MPO−H2O2−Cl- system and ex vivo in human polymorphonuclear leukocytes (PMNs)[4]

 

Biochem/physiol Actions

This antioxidant is found in chocolate. (-)-Epicatechin is linked with cardiovascular effects. It is considered as a dependable standard due to its availability in cacao seeds and cocoa products.[5] The halogenating activity of myeloperoxidase can be restored by (-)-epicatechin.[4]