Sigma-Aldrich® EPPS, ≥99.5% (titration), 250G

MT-CM-E9502-250G

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Empirical Formula (Hill Notation): C9H20N2O4S

CAS Number: 16052-06-5

Molecular Weight: 252.33

Beilstein: 3957385

EC Number: 240-198-8

MDL number: MFCD00006160

UNSPSC Code: 12161700

PubChem Substance ID: 24894698

NACRES: NA.25

Quality Level: 400

Assay: ≥99.5% (titration)

Form: powder

pH: 7.3-8.7

useful pH range: 7.3-8.7

pKa (25 °C): 8.0

pKa : 8

mp: 237-239 °C (lit.)

solubility: H2O: 25 g + 50 mL, clear, colorless

λmax: A290 at ≤0.1 (C=33% w/w)

application(s): diagnostic assay manufacturing

SMILES string: OCCN1CCN(CCCS(O)(=O)=O)CC1

InChI: 1S/C9H20N2O4S/c12-8-7-11-5-3-10(4-6-11)2-1-9-16(13,14)15/h12H,1-9H2,(H,13,14,15)

InChI key: OWXMKDGYPWMGEB-UHFFFAOYSA-N

Application

EPPS has been used:

to verify the effect of pH variation on the proteolytic activity of the posterior midgut (PMG) contents and anterior midgut (AMG) tissue homogenate
to prepare a destaining buffer to destain intensely stained gel pieces
to prepare digestion buffer for in-gel enzymatic digestion
to reconstitute the digested peptides for the processing of brain-derived extracellular vesicle (EV) proteins and 16-plex isobaric tandem mass tag (TMT) peptide labeling