General description
Propidium iodide (PI) is a fluorescent dye thatcan be used
for staining nucleic acids.[1] It is impermeable in viable orintact cells.
It can penetrate easily into dead, dying, or
membrane-compromisedcells.[1][2] PI has the capacity to bind easily to
DNA.[3]
Application
Propidiumiodide has been used: to detect cell cycle by flow
cytometry and γH2AXand pH3 analysis[4],apoptosis assay in hepatic stellate
cells (HSCs)[5], in stainingbuffer/solution to stain the cells for cell cycle
analysis[6]
Features and Benefits
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Other Notes
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