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Supelco® Clindamycin hydrochloride, Pharmaceutical Secondary Standard

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Empirical Formula (Hill Notation):  C18H33ClN2O5S · HCl · H2O

CAS Number:  58207-19-5

Molecular Weight:  479.46

UNSPSC Code:  41116107

NACRES:  NA.24

Grade:

certified reference material

pharmaceutical secondary standard

Quality Level:  300

Agency:

traceable to Ph. Eur. C225000

traceable to USP 1136002

API family:  clindamycin

CofA:  current certificate can be downloaded

technique(s):

HPLC: suitable

gas chromatography (GC): suitable

application(s):  pharmaceutical (small molecule)

format:  neat

storage temp.:  -10 to -25°C

SMILES string:

S([C@H]1O[C@@H]([C@@H]([C@@H]([C@H]1O)O)O)[C@H](NC(=O)[C@H]2[N+H](C[C@@H](C2)CCC)C)[C@@H](Cl)C)C.[Cl-].O

InChI:

1S/C18H33ClN2O5S.ClH.H2O/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H;1H2/t9-,10+,11-,12+,13-,14+,15+,16+,18+;;/m0../s1

InChI key:  KWMXKEGEOADCEQ-WNNJHRBUSA-N

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Clindamycin is a common antibiotic drug generally employed for the treatment of infections caused by gram-positive aerobes and both gram-negative and gram-positive anaerobic pathogens.[1]

Application

Clindamycin hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography[2][1] and potentiometry[3] techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAB7830 in the slot below. This is an example certificate only and may not be the lot that you receive.

Values of analytes vary lot to lot.