General description
Polyvinylpyrrolidone (PVP) can form complexes with phenolics
and alkaloids. The complex formation allows removal of phenolics and alkaloids
from plant samples, thereby inhibiting any modification of proteins by them and
any hindrance they may cause in spectrophotometric determinations of protein
content. PVP might also enhances the stability of enzymes.[1]
Polyvinylpyrrolidone (PVP), a multifunctional synthetic
polymer, finds utility in life science and biochemical research. This
water-soluble polymer is versatile, serving as a stabilizing agent, emulsifier,
suspending agent, solubilizing agent, protective colloid, and complexing agent.
Its protective colloid properties are particularly valuable in stabilizing
proteins, enzymes, and other biological substances.
Application
Polyvinylpyrrolidone has been used in the purification of
glutamine synthetases from plant samples.[2] It has been used to block the
PVDF (polyvinylidene difluoride) membrane and to avoid nonspecific
binding.[3][4]
Features and Benefits
- Highly
versatile surfactant for your life science and biochemical research
- Excellent
Solubilizing agent and Complexing agent
Other Notes
For additional information on our range of Biochemicals, please complete this form.
Polyvinylpyrrolidone is a component of Denhardt′s Solution
and is included at a concentration of 1% (w/v) in the standard 50X stock
solution.
