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  3. Sigma-Aldrich® Trichloroacetic acid ACS reagent grade, ≥99.0% 250G

Sigma-Aldrich® Trichloroacetic acid ACS reagent grade, ≥99.0% 250G

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MT-CM-T6399-250G

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Linear Formula:  Cl3CCOOH

CAS Number:  76-03-9

Molecular Weight:  163.39

Beilstein:   970119

EC Number:  200-927-2

MDL number:  MFCD00004177

UNSPSC Code:  12352100

PubChem Substance ID:  24900373

NACRES:  NA.21

Product Name:  Trichloroacetic acid, ACS reagent, ≥99.0%

Grade:  ACS reagent

Quality Level:  200

vapor density:  <1 (vs air)

vapor pressure:  1 mmHg ( 51 °C)

Assay:   ≥99.0%

Impurities:

Substances darkened by sulfuric acid, passes test

≤0.01% insoluble matter

ign. Residue:  ≤0.03%

refractive index:  n20/D 1.62 (lit.)

bp:  196 °C (lit.)

mp:  54-58 °C (lit.)

solubility:  H2O: 1 g/10 mL

density:  1.62 g/mL at 25 °C (lit.)

anion traces:

chloride (Cl-): ≤0.002%

nitrate (NO3-): ≤0.002%

phosphate (PO43-): ≤5 ppm

sulfate (SO42-): ≤0.02%

cation traces:

Fe: ≤0.001%

heavy metals (as Pb): ≤0.002%

functional group:

carboxylic acid

chloro

storage temp.:  2-8°C

SMILES string:  OC(=O)C(Cl)(Cl)Cl

InChI:  1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI key:   YNJBWRMUSHSURL-UHFFFAOYSA-N

Application

  • Trichloroacetic acid has been used for the precipitation of sLRP (soluble circulating low density lipoprotein receptor-related protein-1) isolated from plasma.[1]
  • It has been used for the extraction of ascorbic acid from plant samples. It has also been used for the preparation of ascorbate standards for ascorbate assay.[2]
  • It has been used for the precipitation of IMAC (immobilized metal ion affinity chromatography)-isolated phosphoproteins.[3]

Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.