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  2. Sigma-Aldrich® L-Tryptophan 99.0-101.0%, suitable for cell culture, BioXtra, non-animal source

Sigma-Aldrich® L-Tryptophan 99.0-101.0%, suitable for cell culture, BioXtra, non-animal source

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Empirical Formula (Hill Notation):  C11H12N2O2

CAS Number:  73-22-3

Molecular Weight:  204.23

Beilstein:  86197

EC Number:  200-795-6

MDL number:  MFCD00064340

UNSPSC Code:  12352209

eCl@ss:  32160406

PubChem Substance ID:  24900575

NACRES:  NA.26

Product Name:

L-Tryptophan, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%

biological source:  non-animal source

Quality Level:  300

Agency:

USP/NF

meets EP testing specifications

meets JP testing specifications

meets USP testing specifications

product line:  BioXtra

Assay:  99.0-101.0%

Form:  powder

Quality:  meets EP, JP, USP testing specifications

technique(s):  cell culture | mammalian: suitable

impurities:  endotoxin, tested

color:  white to yellow

mp:  280-285 °C (dec.) (lit.)

solubility:  1 M HCl: 10 mg/mL

application(s):  pharmaceutical (small molecule)

SMILES string:  N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI:  1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1

InChI key:  QIVBCDIJIAJPQS-VIFPVBQESA-N

Application

L-Tryptophan has been used in PreC media preparation and in cell culture.[1][2]

Biochem/physiol Actions

Tryptophan (Trp) is one of the functional amino acids that is associated with growth, reproduction, maintenance and immunity.[3] Increased Trp availability is necessary for the regulation of mood, cognition and behaviour. It is hypothesised that L-Trp might be useful in inducing sleep in healthy adults against the normal circadian rhythm. Trp uptake by the brain depends on the plasma ratio of Trp to all of the other LNAAs (large neutral amino acids). Higher the Trp:LNAAs ratio, greater is the Trp uptake.[4]

Other Notes

Amino acid precursor of serotonin and melatonin